Clean and well-groomed skin is considered a sign of human health. People with problem skin, especially in adolescence, try to get rid of blemishes with the help of various cosmetics and medications.
To combat acne, acne spots or non-allergic rashes, use the drug “Effezel” (gel), a photo of which is presented in the article.
Description
This product is produced in France. Effezel gel has been on the Russian market since 2013, but has already proven itself to be an effective remedy. Its predecessors were the drugs Differin and Baziron AS. The use of these two drugs consisted of alternately applying layers of first one and then the other. This treatment was effective, but required a significant amount of time to be allocated for the procedure.
The duration of the manipulations is associated with the gradual penetration of active substances into the skin. The disadvantage of the treatment was the low rate of penetration of benzoyl peroxide into the skin and its rapid transformation into benzoic acid.
Scientists were able to combine these two drugs into one acne drug, Effezel. It is effectively used at any age to combat acne.
Release form
To find out what the drug “Effezel” is, cream or gel, just look at its instructions for use. The description says that the medicine has an opaque consistency, pale or slightly yellow in color. Available in gel form for external use.
Sold in plastic tubes with a laminated coating of 2, 15, 30, 45, 60 and 90 g. Each tube is packaged in a pack with instructions for use.
Compound
The instructions provide a list of all active and auxiliary components. For the drug "Effezel" (gel), the composition is prescribed for one gram of medicine.
The main active ingredients are adapalene in an amount of 1 ml and 25 mg of benzoyl peroxide.
Excipients include 5 mg of sodium docusate, 1 mg of disodium edetate, 0.4 mg of glycerol, 2 mg of type 124 poloxamer, 0.4 mg of propylene glycol, up to 1 g of purified water and simulgel type 600 RHA. The latter compound consists of 35-40% copolymer of acrylamide and acryloyldimethyl taurate, 20-25% isohexadecane, 5-10% polysorbate, 2.5% sorbitan oleate and water in an amount sufficient to one hundred percent.
Acne treatment with Effezel
The instructions said that the gel should be applied in a thin layer once a day before bed, on previously cleansed skin. No sooner said than done.
On the first day I noticed absolutely nothing, no effect. I was even indignant, like, what is this money for? But it all started the next morning after the second application. My skin became very red, began to dry out, peel, and hurt when touched. I walked around with a face as if I had been seriously burned in a solarium. It is worth noting that it is strictly forbidden to use cosmetics, and in particular foundations, powders, and mattifying creams!
You need to endure for the sake of the effect that awaits you. The only thing I bought was a water-based moisturizer to somehow hide my flaky face (it looked like a snake was shedding its skin).
Analogs
There are drugs on the pharmaceutical market with the same active ingredient in their composition. For the drug "Effezel" (gel), analogues are produced on the basis of adapalene with the same percentage.
One of these drugs is Adapalene gel, intended for external use in the treatment of acne. The amount of adapalene is 0.1%, sold in 30 g tubes.
Another similar drug is Differin gel or cream at a dosage of 0.1%, which is considered a precursor to the two-component Effezel (gel). Produced in French in tubes of 30 g.
The medicine “Effezel” (gel) can have analogues not only from Europe, but also from India, for example, 0.1% gel for external use “Klenzit”, produced by. It is produced in two packages of 15 and 30 g in the form of a white gel-like homogeneous liquid.
Another Indian analogue is the drug “Adaklin”, available in the form of a 0.1% cream for external use. The product has a homogeneous white creamy texture. As in other analogues, the active ingredient is the dermatoprotective substance adapalene.
Acne gel "Effezel" can be replaced with the Russian drug "Adolen". The medicine is produced at Sintez OJSC in two packages of 15 and 30 g.
Effezel gel: reviews
Thanks to this drug, I got rid of acne forever . For about 2 years I had a lot of problems with acne. At first I noticed them on my forehead, then they spread to my cheeks, and later they began to cover my entire face. Whatever drugs I used, they did not lead to positive results. But one day I learned from a doctor about the product Effezel Gel, which was prescribed to me.
When I decided to use it, I didn’t think it would help. However, after some time, I began to observe positive changes: the number of acne decreased each time. Gradually, my confidence in my own abilities returned, and I continued to use this drug, although it caused me a lot of discomfort . I steadfastly endured the itching of the skin, the effect of dryness and flaking, but it was worth it: soon there was not a single pimple left on my skin. If you have been suffering from the same problem for a long time, then I recommend using this ointment, it will be an effective solution to the problem for you.
Zhenya
I became acquainted with this drug thanks to my attending physician. When using it, I was convinced of its effectiveness. From my own experience, I can say that I have never achieved such positive results before. After the first week of using the gel, I began to notice positive changes. After just two weeks, I noticed that my skin had acquired a clean and smooth appearance, and there was no trace of acne left.
To be honest, I didn’t expect this drug to change my face so much. Despite all its advantages, this gel also has disadvantages: its price is quite high , and after a certain period of using the product, the skin becomes too dry. But despite this, you should not give up this drug. I suffered from acne for a long time, and finally I found the only remedy that helped me. Therefore, my review will be positive: although it is quite expensive, its price fully corresponds to the result.
Hope
This gel does not live up to all the positive reviews that are written about it. I only used it for a few weeks and it didn't help me , it just caused me a lot of inconvenience. Because of him, I kept tossing and turning in my sleep. However, it caused the greatest problems to my skin, which was constantly burning, flaking and dry. As a result, I stopped using it pretty soon, and I don’t plan on going back to it.
Valentine
How it works
The instructions for use for the product “Effezel” (gel) describe the mechanism of influence of its active components on problem areas of human skin. It has been proven that the two active ingredients included in the gel exhibit different but complementary properties.
Adapalene refers to one of the naphthoic acid derivatives, which has retinoid-like effects and chemical stability. The substance has a pathogenetic effect against the causative agents of acne vulgaris, actively modulates cell differentiation and keratinization, and exhibits an anti-inflammatory effect.
Adapalene binds specific nuclear receptors for retinoic acid. The local use of the drug has been studied, during which the differentiation of follicular epithelial cells is normalized, which prevents the development of microcomedones. Test-tube studies have shown that under the influence of adapalene, human polymorphonuclear leukocytes reduce the response of a chemotactic (directed) and chemokinetic (voluntary) nature, the metabolism of arachidonic acid and the synthesis of mediators responsible for inflammation are inhibited. This results in a reduction in the cell-mediated inflammatory component of acne.
Benzoyl peroxide has an exfoliating and keratolytic effect, an antimicrobial effect in the presence of Propionibacterium acne, located in the sebaceous pilosebaceous follicles of acne. The substance exhibits a sebostatic effect, preventing excessive secretion of the sebaceous glands and aggravating the rash.
Results from using Effezel gel
Already after the first application of the product, you can notice positive changes , as indicated by reviews. This will result in a reduction in inflammation on the facial skin. After two days, you can observe how the acne begins to dry out. When there is not a single pimple left on the skin, the process of skin restoration and healing of the upper dermis will begin.
A month after the first use of the product, provided it is applied regularly, the number of comedones will also begin to decrease . The person himself determines the duration and intensity of treatment with this drug, paying attention to the intensity of the skin disease. After 1-4 weeks from the moment of first use of the drug, the therapeutic effect will begin to manifest itself.
If improvements are observed, and the amount of acne decreases, then it is permissible to reduce the number of procedures to 1 time every 2 days. Sometimes the skin may become dry and red after such procedures.
When do acne go away?
If you look at the research results, you can completely get rid of acne with regular use of Effezel gel if this product is used for 52 weeks . There are many reviews that the product demonstrates high effectiveness with long-term use, and bacteria cannot adapt to its effects and continue to die. According to the results of clinical studies, long-term use of this gel does not cause any harm to health.
You can stop using the product only if you observe allergic manifestations caused by one of the components contained in the effezel gel. This may include swelling of the skin, mouth, lips, signs of burning, itching and tingling. In case of such symptoms, the product must be washed off immediately, the remaining drug must be removed from the skin, after which the patient must take antiallergic medications or visit a doctor.
Rules for proper application
The essence of the procedure for applying the gel is as follows: using soft fingertips, you need to lubricate the entire affected area . When a thin film of gel appears on the skin, you need to wait a while for the drug to be absorbed. For this reason, it is recommended to perform a similar procedure before going to bed. Effezel gel can be used as a base for makeup, on which foundation can be applied. Moreover, this will in no way affect the properties of the drug.
What is it used for?
Skin problems in the form of acne occur when the exfoliation of dead cells is slowed down and sebum is produced at the same rate. The result is the formation of a new epithelial layer, not cleared of dead cells, but already with accumulated secretion from the sebaceous glands. Sebum has nowhere to escape from the confined space, and the process of inflammation begins.
To prevent congestion on the skin, drugs are needed that accelerate the differentiation of epithelial cells and reduce the secretion of sebaceous glands. Effezel (gel) has this effect Instructions for use recommend using it for topical treatment of acne.
The effectiveness of acne therapy with the formation of comedones, papules and pustules has been proven. “Effezel” gel is used for acne spots that make the skin unsightly.
How to use
Apply Effezel gel with your fingertips to form a thin film over the entire affected surface. The procedure is carried out once a day in the evening, the skin should be clean and dry, the medicine should not penetrate the mucous membranes of the body.
The therapeutic effect begins to appear after 7 days of treatment. The duration is determined by the doctor after examining and identifying the patient’s disease.
If irritation occurs on the skin, use non-comedogenic products with a moisturizing effect and reduce the number of applications every other day. Depending on the degree of the adverse reaction, treatment is suspended until signs of allergy are eliminated or stopped altogether.
Effezel gel: instructions for use
- Before lubricating your skin with this product, you must first clean it and then dry it. Only intact and undamaged skin is suitable for applying this product. It is unacceptable to treat skin with abrasions, cuts, or areas that have been sunburned with Effezel gel. Also, areas such as eyes, lips and ears, as well as eczema and any mucous membranes, should not be applied.
- Even before using the product, you need to find out how the skin reacts to the gel. To do this, apply it in a small amount to an area of skin and then allow it to absorb for 20-30 minutes. You should proceed to direct treatment of acne only if there is no negative reaction from the treated skin. It is not recommended to use Effezel gel in combination with abrasive medicinal soaps, cosmetics that have a strong drying effect, or those containing acids, alcohols and astringents.
- It should be borne in mind that the product should be used only with a certain frequency: it is optimal if it is used no more than once a day. Usually the entire surface of the face is treated with gel. But in some cases, you can apply it only to the area where there are acne. For this purpose, you can use not only Effezel gel, but also the drug Baziron.
Features of application
The drug "Effezel" (gel) does not treat skin with damage caused by trauma, for example, cuts or abrasions of the epithelium. It is not recommended to apply the medicine to eczematous skin.
Contact with the mucous membrane of the eyes, mouth, nostrils and other areas covered with mucus is unacceptable. Accidental contact of the gel with the eyes requires immediate rinsing with plenty of warm water.
The drug contains propylene glycol, or E1520, which can cause skin irritation. If there are signs of hypersensitivity to the components of the drug, the use of Effezel (gel) should be discontinued.
During treatment, it is necessary to limit exposure to sunlight or ultraviolet radiation on the affected areas.
The drug can change the color or completely discolor colored materials, such as hair or clothing, so when using the gel should not be allowed to come into contact with them.
The existing experience with the use of drugs based on benzoyl peroxide and adapalene has shown that when combined with other medications, there are no signs of interaction. However, in order to avoid enhanced effects, the manufacturer does not recommend the simultaneous use of Effezel gel with other retinoids, benzoyl peroxide, or with drugs that exhibit a similar effect.
Caution should be used in combination with cosmetics that have an exfoliating and drying effect to avoid excessive irritation.
The rate of absorption of adapalene through skin cells is low, which explains the low likelihood of interaction with systemic medications.
Benzoyl peroxide slowly penetrates the skin and is completely converted into benzoic acid, which can be quickly excreted from the body. This explains the lack of interaction between benzoic acid and drugs in the systemic circulation.
When will the effect appear?
Noticeable skin changes can be observed when using the drug "Effezel" (gel). Photos before and after use indicate the effectiveness of the drug in treating acne and acne scars.
However, the process of restoring the skin with the help of adapalene does not occur in one day. It should take from one week to a month of daily procedures using the Effezel gel to notice the result.
This is due to the difficulty of adapalene to penetrate the skin, as well as due to its rapid elimination from the human body. Gel therapy is long-term with a cumulative effect. The period of manipulation can take up to six months. To consolidate the results after a course of treatment, regular skin peeling is necessary; you can do it yourself at home.
Side effects
As it is written in the instructions and on numerous forums with websites. The skin is addictive to Effezel (it is a side effect of the drug), and it is quite long-lasting. In my case it lasted for three weeks. For all three weeks I suffered terribly from redness, burning and dryness. I was even scared that the gel simply wasn’t suitable for me and wanted to quit.
But as soon as I remembered its price and what I started all this for, I decided to endure it to the end. By the end of the third week, the dryness began to subside, the redness and irritation went away, and I boldly removed the remaining peeling with a finely abrasive scrub. It is also worth mentioning that if you are going to apply the gel in the summer, be sure to protect your face with high UVF sunscreen!
