Comparison of the effectiveness of Exoderil and Mycospor
The effectiveness of Exoderil is quite similar to Mycospor - this means that the ability of the drug substance to provide the maximum possible effect is similar.
For example, if the therapeutic effect of Exoderil is more pronounced, then using Mycospor even in large doses will not achieve this effect.
Also, the speed of therapy - an indicator of the speed of therapeutic action - is approximately the same for Exoderil and Mikospor. And bioavailability, that is, the amount of a drug reaching its site of action in the body, is similar. The higher the bioavailability, the less it will be lost during absorption and use by the body.
Properties of Exoderil
Exoderil is an antifungal drug from an Austrian manufacturer. It also contains naftifine (in the form of hydrochloride). The concentration of the active ingredient may vary depending on the dosage form. The cream and solution have antimycotic, fungistatic and fungicidal effects. The topical antimycotic belongs to the group of allylamines - it inhibits the biosynthesis of ergosterols, which are part of the cell wall of fungi.
The drug is active against trichophytons and epidermophytons. Can be used as part of complex therapy against yeast and mold fungi. It has a fungicidal effect on dermatophytes and aspergilli, and a fungistatic effect on yeast fungi. For therapeutic and preventive purposes, Exoderil is used for pityriasis versicolor, candidiasis, dermatomycosis and hyperkeratosis.
The drug Exoderil is active against trichophytons and epidermophytons.
In order to stop the spread of fungal infection, Exoderil must be applied at least once a day to the affected areas of the skin. If necessary, you can grab healthy parts of the skin (along the edges of the lesion). Before applying the solution or cream, the skin must be cleaned of dirt and dried.
If the nail plates are affected, the solution is applied 2 times a day, before this the affected part of the nail is removed with a file.
Comparison of the safety of Exoderil and Mycospor
The safety of a drug includes many factors.
At the same time, in Exoderil it is quite similar to Mikospor. It is important where the drug is metabolized: drugs are excreted from the body either unchanged or in the form of products of their biochemical transformations. Metabolism occurs spontaneously, but most often involves major organs such as the liver, kidneys, lungs, skin, brain and others. When assessing the metabolism of Exoderil, as well as Mycospor, we look at which organ is the metabolizing organ and how critical the effect on it is.
The risk-benefit ratio is when the prescription of a drug is undesirable, but justified under certain conditions and circumstances, with the obligatory observance of caution in use. At the same time, Exoderil does not have any risks when used, just like Mikospor.
Also, when calculating safety, it is taken into account whether only allergic reactions occur or possible dysfunction of the main organs. In other matters, as well as the reversibility of the consequences of using Exoderil and Mycospor.
Properties of Mikoderil
All dosage forms of Mikoderil are intended for external use. The solution and cream contain naftifine hydrochloride, which belongs to the group of allylamines. The component is capable of selectively inhibiting squalene epoxidases, which reduces the rate of ergosterol formation.
The main substance is active against mold, yeast, and yeast-like fungi. The drug has a fungicidal effect on dermatophytes; on yeast-like and yeast fungi, the active component has a fungistatic or fungicidal effect. Antibacterial activity is visible against gram-positive and gram-negative pathogenic microorganisms that provoke the development of infection.
Both dosage forms can be used for fungal infections of skin folds and smooth skin, candidiasis, inflammatory dermatomycosis, interdigital mycoses. The solution is approved for use against scalp fungus.
Mikoderil has a pronounced antipruritic property, which allows it to be used for irritation caused by fungus. Naftifine, which is part of it, eliminates itching and swelling. When applied externally, regardless of the form of release, the product quickly penetrates the skin and acts on pathogenic microorganisms. Due to the optimal concentration, the active substance is stored in different layers of the skin for a long time, so the drug can be applied once a day.
It is absorbed slightly, a small part (no more than 6%) undergoes partial metabolism. The half-life is 48-72 hours, excreted in urine and feces.
Comparison of addiction between Exoderil and Mycospor
Like safety, addiction also involves many factors that must be considered when evaluating a drug.
So, the totality of the values of such parameters as “syndrome o” in Exoderil is quite similar to the similar values in Mikospor. Withdrawal syndrome is a pathological condition that occurs after the cessation of intake of addictive or dependent substances into the body. And resistance is understood as initial immunity to a drug; in this it differs from addiction, when immunity to a drug develops over a certain period of time. The presence of resistance can only be stated if an attempt has been made to increase the dose of the drug to the maximum possible. At the same time, Exoderil has quite a small amount of “syndrome”, just like Mikospor.
Brief characteristics of the cream "Mikoderil"
The cream is produced in soft metal tubes weighing from 10 to 100 g , placed in a cardboard box. This is a white substance that has a viscous consistency and a specific odor.
Indications:
- Mycosis of smooth skin.
- External candidiasis.
- Tinea versicolor.
- Onychomycosis (nail fungus infection).
- Various forms of interdigital mycoses.
Contraindications:
- Hypersensitivity to any of the components.
- The period of pregnancy and breastfeeding.
- Use of the product on open wound surfaces.
Mode of application
For fungal skin infections, Mycoderil cream is applied once a day . Before using the drug, this area of skin should be cleaned and dried thoroughly. When applying the cream, you should cover not only the lesion itself, but also the healthy skin around it within one centimeter.
For onychomycosis, the cream must be used twice a day. Before starting to use this medicine, areas of the nails that have been affected by fungus should be removed if possible. Treatment of onychomycosis can be very long, but it is not recommended to use this remedy for more than six months. After the symptoms disappear, the cream must be applied for another two weeks to prevent relapse of the disease.
Comparison of side effects of Exoderil and Mycospor
Side effects or adverse events are any adverse medical event that occurs in a subject after administration of a drug.
Exoderil's side effects are almost the same as Mikospor's. They both have few side effects. This implies that the frequency of their occurrence is low, that is, the indicator of how many cases of an undesirable effect of treatment are possible and registered is low. The undesirable effect on the body, the strength of influence and the toxic effect of Exoderil are similar to Mycospor: how quickly the body recovers after taking it and whether it recovers at all.
Spray
Mycostop spray is an excellent preventative against nail fungus. In addition, it can be used if your feet sweat a lot. It can be used to process shoes, socks or tights. The spray is also applied to the feet or nails if there is contact with objects that are potential carriers of the fungus.
Considering the presence of aromatic compositions in the spray, Mycostop deodorant also copes well with eliminating unpleasant odors.
The instructions for use of the spray recommend using it in the following cases:
- for disinfection of shoes in the treatment and prevention of fungus;
- for the purpose of preventing foot and nail fungus;
- to eliminate sweaty feet.
Avoid contact of the product with mucous membranes and the eye area. If this happens, you must rinse them thoroughly with cool running water. In case of inflammation, you need to seek medical help.
Comparison of ease of use of Exoderil and Mycospor
This includes dose selection taking into account various conditions and frequency of doses. At the same time, it is important not to forget about the release form of the drug; it is also important to take it into account when making an assessment.
The ease of use of Exoderil is approximately the same as that of Mycospor. However, they are not convenient enough to use.
The drug ratings were compiled by experienced pharmacists who studied international research. The report is generated automatically.
Last update date: 2020-12-04 13:42:12
Brief characteristics of the Mycoderil solution
The solution is packaged in bottles with a special dropper. This is a transparent, colorless substance that has the smell of ethyl alcohol.
Indications and contraindications
The solution is used for the same diseases as the cream. However, there is an additional indication for it: fungal infections of the scalp. Contraindications are the same as for the cream.
Mode of application
The product is applied using a dropper with a dispenser . For nail fungus, a previously prepared (steamed and filed) nail plate is treated. The drug must also be applied under the nail. This way the drug will work directly at the source of infection.
Mikoderil for nail fungus
Many effective drugs have been created for the treatment of nail fungus, and one of them is Mikoderil, which is developed by analogy with the popular imported drug Exoderil. We invite you to learn about the features of its use for onychomycosis.
Composition, release form and price
The active ingredient of Mikoderil is naftifine hydrochloride. The drug is produced in Russia. Available in two forms:
- Cream. The concentration of the active substance is 1%. It has a homogeneous substance. Packaged in tubes of 15 g. The price in Russia is 362 rubles, in Ukraine - from 170 hryvnia.
- Solution. External remedy. Contains 1% active ingredient. Packaged in bottles of 10 and 20 ml. The drug in liquid form has a pronounced odor of alcohol. Buy drops The cost of the product in Russian pharmacies is 468 rubles. for 10 ml and 756 rub. for 20 ml, in Ukrainian - 280 hryvnia.
We will talk more about the composition of the drug in the table.
Release formList of included components
| CREAM 1% |
|
| SOLUTION 1% |
|
Operating principle
In addition, Mikoderil has a symptomatic effect, quickly relieving the inflammatory process at the site of infection, eliminating itching, swelling and other signs of onychomycosis.
The principle of pharmacological action of all forms of drug release is based on antibacterial, antimicrobial and fungistatic mechanisms. This effect is achieved through the ability of Mikoderil to inhibit the production of ergosterol by the cells of pathogenic microorganisms and at the same time produce squalene, which leads to the massive death of all known species of fungi and their mycospores.
Indications
The drug can be used to treat various mycotic lesions of the skin and nails. Let's consider the main conditions for which the use of Mikoderil is recommended:
- pityriasis versicolor;
- interdigital mycoses;
- dermal candidiasis;
- skin and nail fungus.
Instructions for use
It is recommended to use Mikoderil for onychomycosis in combination with other medications and folk remedies. A comprehensive solution to the problem guarantees a high chance of recovery. If the pathological process has led to damage not only to the nail plate, but also to the skin of the feet, Mikoderil cream must be combined with the use of a solution of the same name.
The active components of the liquid form of the drug penetrate deeply into infected tissues, destroying the pathogens of onychomycosis inside, and the cream stops the reproduction and spread of fungal microflora outside. The duration of use of Mikoderil depends on the specific clinical situation. Let's look at the features of using the drug in the table.
Release formInstructions
| CREAM | The medicine is applied to previously prepared nail plates, covering the infected area and 1 cm of tissue near it. The procedure is carried out 2 times a day until a healthy nail grows. After the symptoms of the pathology disappear, the product must be used for another 14 days as a prophylactic measure to avoid relapse of the infection. |
| SOLUTION | Like the previous form of Mikoderil, the solution is recommended to be applied to the foci of onychomycosis 2 times a day. The course of treatment depends on the stage of the disease, but its duration should not exceed 6 months. |
Before using Mikoderil, the treatment area - the nail plates - should be prepared accordingly. The feet or hands are dipped into a hot bath with the addition of softening ingredients (laundry soap, salt or soda) for steaming and subsequent cleansing of exfoliated tissues affected by onychomycosis.
The effectiveness of the drug in advanced stages of onychomycosis
Local medications, regardless of pharmacological composition, cannot cope with long-standing infection. Their method of application should be combined with systemic antimycotics that work in the body from the inside. Only an integrated approach guarantees a solution to the problem of advanced onychomycosis.
Use for children, pregnant and lactating women
Mikoderil, as well as other drugs based on naftifine hydrochloride, are contraindicated for women during pregnancy and lactation. Also, a similar restriction applies to children under 18 years of age.
This is due to the unstudied effect of the active component of the drug on the patient’s body in these cases.
Side effects, contraindications
Before starting treatment for onychomycosis with Mikoderil cream or solution, the patient should be aware of the unwanted reactions that the drug can provoke. So, the use of the drug sometimes causes the following symptoms:
- burning;
- dryness;
- hyperemia;
- swelling.
As a rule, all of the listed signs of trouble disappear on their own within a short time, and, in this case, their appearance should not serve as an indication for stopping the medication.
In the opposite situation, if the symptoms increase and are aggravated by additional problems, it is important to refuse further use of Mikoderil for therapeutic purposes, since most likely we are talking about an allergic reaction.
The drug is not recommended for use in the following cases:
- individual hypersensitivity to individual components of Mikoderil;
- pregnancy, breastfeeding;
- open wound surfaces of any nature;
- children under 18 years of age.
Mikoderil solution or cream - which is better?
Both drugs contain the same active ingredient, but have a different principle of activity against nail fungus.
The solution is, in fact, a liquid that, thanks to its release form, more easily penetrates into the deep layers of the skin and nails, where it destroys pathogenic microflora. The drug is easily applied to the foci of onychomycosis using a dropper bottle, covering the plate like a medicinal varnish.
The cream has a denser structure, so it is more difficult to absorb into fabrics, remaining mainly on the surface. It is here that it destroys fungal spores, preventing them from multiplying and spreading to healthy areas of the body.
Mikoderil or Exoderil, which is more effective?
Both medications contain the same active ingredient - naftifine hydrochloride. That is, the principle of operation of the drugs is identical, as are the possible side effects and the list of contraindications.
