Pharmacological properties of the external preparation
How does Azix-derm work? The instructions state that this drug has a moderate cytostatic effect. This occurs due to the inhibition of cell protein synthesis, and is manifested in the normalization of keratinization processes in the walls of the sebaceous gland follicles.
What properties does Azix-derm cream have? Reviews from doctors inform patients that it has an antimicrobial effect, which is primarily aimed at Staphylococcus epidermidis and Propionibacterium acnes.
The drug is used as an anti-inflammatory agent that acts on both the surface of the skin and the sebaceous glands. It reduces the metabolism of neutrophil granulocytes, as well as the production of free radical oxygen species, that is, important factors in maintaining inflammatory reactions.
With long-term use of the cream, microorganism resistance does not develop. The active substance of the drug dose-dependently inhibits the viability and growth of abnormal melanocytes. The high effect of the drug (for hyperpigmentation) is due to the suppression of the respiration of abnormal melanocyte cells, as well as the inhibition of DNA synthesis.
For rosacea, the therapeutic effect of the drug is associated with a decrease in the formation of anti-inflammatory reactive oxygen radicals.
Comparison of the effectiveness of Skinoren and Effezel
Effezel is more effective than Skinoren - this means that the ability of the drug substance to provide the maximum possible effect is different.
For example, if the therapeutic effect of Effezel is more pronounced, then with Skinoren it is impossible to achieve this effect even in large doses.
Also, the speed of therapy is an indicator of the speed of the therapeutic action; Effezel and Skinoren are also different, as is bioavailability - the amount of a drug reaching the site of its action in the body. The higher the bioavailability, the less it will be lost during absorption and use by the body.
Azix-derm cream: instructions for use
How should the drug in question be used? The cream is applied only externally (to the skin).
The maximum duration of treatment with this drug depends on the characteristics of the patient’s body, the individual picture of the existing disease, as well as the severity of the symptoms. Therefore, this drug should be used only as prescribed by a specialist.
For adults, as well as children over 12 years of age, the medication is applied evenly (in a thin layer) twice a day (in the morning and before bedtime). In this case, the skin is pre-cleaned with hypoallergenic products or plain water.
Before applying the medicinal cream, areas of the skin of the neck, face or upper chest that are affected by acne must be dried.
In what dose is Azix-derm used? Reviews from experts inform patients that it is enough to apply only 2.5 cm of cream to the entire face.
The medication must be used regularly throughout the course of therapy. However, its duration depends on the severity of the disease.
The minimum duration of treatment for melasma is about 3 months. During the treatment of this disease, it is necessary to use sunscreens (type UV A and UV B). This is done in order to prevent exacerbation of the disease or re-pigmentation of the skin under the influence of direct sunlight.
People with acne vulgaris experience noticeable improvement in approximately 4-5 weeks. To achieve the best results, use of the medication should be continued for several months.
Comparison of ease of use of Skinoren and Effezel
This includes dose selection taking into account various conditions and frequency of doses. At the same time, it is important not to forget about the release form of the drug; it is also important to take it into account when making an assessment.
The ease of use of Skinoren is approximately the same as that of Effezel. However, they are not convenient enough to use.
The drug ratings were compiled by experienced pharmacists who studied international research. The report is generated automatically.
Last update date: 2020-12-04 13:42:49
Breastfeeding period and pregnancy
Is it possible to use Azix-derm cream during pregnancy? The composition of this medication is such that during pregnancy it is used only if the expected benefit to the expectant mother significantly outweighs the likely risk to the baby. It should also be noted that it is necessary to avoid applying the drug to the mammary glands during breastfeeding. Otherwise, this can lead to serious consequences.
Side effects after using the drug
Do adverse events occur after using the drug "Aziks-derm"? Reviews from patients and specialists say that often this drug causes skin irritation, as well as hyperemia, erythema, burning sensation, itching and peeling. As a rule, such effects are observed at the very beginning of therapy. They usually go away on their own with further treatment.
In addition to the above, patients may also experience allergic reactions (for example, rash). Also, after applying the drug to the skin of the face, a feeling of tingling and burning often occurs. However, it should be noted that such sensations disappear on their own within ¼ hour.
Comparison of safety of Skinoren and Effezel
The safety of a drug includes many factors.
At the same time, in Skinoren it is quite similar to Effezel. It is important where the drug is metabolized: drugs are excreted from the body either unchanged or in the form of products of their biochemical transformations. Metabolism occurs spontaneously, but most often involves major organs such as the liver, kidneys, lungs, skin, brain and others. When assessing metabolism in Skinoren, as well as in Effezel, we look at which organ is the metabolizing organ and how critical the effect on it is.
The risk-benefit ratio is when the prescription of a drug is undesirable, but justified under certain conditions and circumstances, with the obligatory observance of caution in use. At the same time, Skinoren does not have any risks when used, just like Effezel.
Also, when calculating safety, it is taken into account whether only allergic reactions occur or possible dysfunction of the main organs. In other matters, as well as the reversibility of the consequences of using Skinoren and Effezel.
Special recommendations for using the cream
What does a patient need to know before using Azix-derm? Reviews from doctors say that it is necessary to avoid contact with the eyes and mucous membranes of the mouth and nose. If such an effect does occur, then it is necessary to immediately rinse the listed parts of the face with a large volume of warm water.
In case of pronounced irritation of the skin in the first days of treatment, Azix-derm cream is recommended to be used once a day or to reduce the amount of the drug used. It is also possible to discontinue the medication for a short time.
After all signs of skin irritation have disappeared, it is necessary to resume regular use of the drug in the dosage recommended by the doctor.
According to experts, dermal melasma is insensitive to therapy with the drug in question. To carry out differential diagnosis, a Wood's lamp is used.
Azix-derm cream can be used in combination with other methods of treating acne and other skin problems. At the same time, you can easily adjust the dosage regimen of all other medications.
The drug "Azix-derm" is not able to have any effect on a person’s ability to drive vehicles or operate other complex mechanisms.
Comparison of side effects of Skinoren and Effezel
Side effects or adverse events are any adverse medical event that occurs in a subject after administration of a drug.
Effezel has more adverse effects than Skinoren. This implies that the frequency of their occurrence is low in Effezel and low in Skinoren. Frequency of manifestation is an indicator of how many cases of an undesirable effect from treatment are possible and registered. The undesirable effect on the body, the strength of influence and the toxic effect of drugs are different: how quickly the body recovers after taking it and whether it recovers at all. When using Effezel, the body's ability to recover faster is higher than that of Skinoren.
Analogues of the external product and its price
What can replace Azix-derm? This drug has several analogues. The most well-known include the external gel “Azelik”, as well as medications such as “Skinoren” and “Skinoklir”. These products can be purchased at any pharmacy. However, it should be noted that Azix-derm can be replaced with them only after consultation with a specialist.
How much does the drug in question cost? Its price is quite high. For 30 g of 20% cream you will have to pay about 650 Russian rubles. It should also be noted that analogues of this medication are no less expensive. Gel "Azelik" in the same volume can be bought for 670-680 rubles, and "Skinoren" and "Skinoklir" - for 850 and 830 rubles, respectively.
Patient reviews of the external preparation
What do they say about such an anti-acne product as Azix-derm? Patients leave only positive reviews about him. They claim that this medication quite effectively fights acne, as well as other skin problems. However, this only happens if the drug was used strictly according to indications and as prescribed by a specialist (that is, a dermatologist). It should also be noted that the therapeutic effectiveness of this product appears only after long-term and regular use of the cream.
It should also be said that this drug is rare, but there are still negative reviews. Some patients using the acne remedy have not reported any results. Experts explain this fact by the fact that each person is individual, and the same drug can affect people differently. By the way, among the negative reviews we can also note those that say that Azix-derm cream is a very expensive product.
What to choose?
Skinoren is intended not only for the treatment of acne, blackheads and rosacea. It has a neutralizing effect on the very mechanisms of development of these formations.
The product is often used to maintain skin health after treatment with other drugs, as it helps prevent the appearance of spots after rashes and even out the color of the skin. The effect is noticeable after 2 - 4 weeks of regular use.
Differin is intended directly for the treatment of skin lesions - acne and closed comedones. Features of the use of the drug are as follows:
- long course of therapy - the first results will appear only several months after regular procedures;
- severe redness - the first two to three weeks the skin will get used to the new substance and react to it with dryness, redness and peeling;
- the need for repeated treatment - you need to understand that acne is considered a chronic disease and often after a course of therapy, acne appears again, and therapy has to be repeated;
- the ability to combine with other medications - treatment can be enhanced with other medications, including Skinoren.
Let us emphasize once again that Differin helps to cope with serious acne defects of the skin, and Skinoren is a reliable protection against spots and scars remaining in the place of cured acne and blackheads.
